Friday, November 12, 2010

30 許多藥物的合成乃是結合分子生物學與合成化學而得,抗愛滋病的藥物3’-Azido-2’,3’-dideoxythymidine(AZT)即為其中一項,下列關於AZT的敘述,何者錯誤?
AZT由易被HIV病毒感染的T淋巴球所吸收而轉變為三磷酸根AZT(AZT triphosphate)
HIV病毒的反轉錄酶對於AZT triphosphate有極高的親和力
HIV病毒的DNA進行複製時若3’端加入AZT triphosphate則會終止複製反應
人類T淋巴球的DNA複製酶對AZT triphosphate有高親和力,所以會帶來許多副作用

asnwer is D

if something has 高親和力, it should not bring so much side effect.

it appears that many questions' answer in the board exam can be excluded from on another by studying the answr posted.

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