維生素B6（pyridoxine） 菸鹼酸（niacin）
核黃素（riboflavin） 硫胺（thiamine）
answer is thiamine
Conditions that frequently lead to lactic acidosis include shock, sepsis, thiamine deficiency, diabetic ketoacidosis, and cellular poisoning (eg, cyanide toxicity).
Thiamine deficiency, or beriberi, refers to the lack of thiamine pyrophosphate, the active form of the vitamin known as thiamine (also spelled thiamin), or vitamin B-1. Thiamine pyrophosphate acts as a coenzyme in carbohydrate metabolism through the decarboxylation of alpha ketoacids; it also takes part in the formation of glucose by acting as a coenzyme for the transketolase in the pentose monophosphate pathway. Persons may become deficient in thiamine either by not ingesting enough vitamin B-1 through the diet or by excess use, which may occur in hyperthyroidism, pregnancy, lactation, or fever. Prolonged diarrhea may impair the body's ability to absorb vitamin B-1, and severe liver disease impairs its use.
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