73 可以取代dapsone，治療癩病且血漿中半衰期長達2個月之藥物為：

rifampin ethambutol clofazimine cycloserine

C

DAPSONE + RIFAMPICIN + CLOFAZIMINE

MULTI DRUG REGIMENT FOR LEPROSY

THE ONE WITH THE LONGEST HALF LIFE IS THE CLOFAZIMINE

Mechanism

Clofazimine works by binding to the guanine bases of bacterial DNA, thereby blocking the template function of the DNA and inhibiting bacterial proliferation.^[2][3] It also increases activity of bacterial phospholipase A2, leading to release and accumulation of lysophospholipids,^[2][3] which are toxic and inhibit bacterial proliferation

Metabolism

Clofazimine has a very long half life of about 70 days. Autopsies performed on clofazimine patients have found crystallized clofazimine in the intestinal mucosa,liver, spleen, and lymph nodes.