48 陳先生祖孫三代共有6個人患了阿茲海默症，下列那一種基因突變最有可能？

myelin basic protein基因 apolipoprotein β基因

presenilin基因 NOTCH 3基因

preSENILE-lin = senile alzeheimer

Myelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the central nervous system (CNS). MULTIPLE SCLEROSIS

apolipoprotein β基因: HYPERCHOLESTEROLEMIA, AND MI

NOTCH 3 GENE:

CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) is the most common form of hereditary stroke disorder, and is thought to be caused by mutations of the Notch 3 gene on chromosome 19.