39 一位35歲女性罹患血栓症，下列何者尚不能符合抗磷脂症候群（antiphopholipid syndrome）的診斷條件之一？

 曾有1次測得anticardiolipin IgM antibody呈中度陽性反應

過去曾2次在懷孕第28-30週，因子癇症（eclampsia）造成早產

罹患肝門靜脈血栓

罹患腦動脈血栓

answer A

Criteria

The diagnosis of APS is made in case of a clinical event (vascular thrombosis or pregnancy event) and repeated positive tests of aPL performed 12 weeks apart (repeat aPL testing is necessary due to the naturally occurring presence of transient low levels of aPL following infections).

The Updated Sapporo APS Classification Criteria (1998, published in 1999) are commonly used for APS diagnosis.^[3] Based on these criteria, APS diagnosis requires:

• a) Vascular Thrombosis (blood clots) in any organ or tissue or Pregnancy Event (one or more miscarriages after 10th week of gestation, three or more miscarriages before 10th week of gestation, or one or more premature births before 34th week of gestation due to eclampsia) and
• b) Persistently (6 weeks apart) Positive aPL (lupus anticoagulant test, moderate-to-high titer anticardiolipin antibodies, or moderate-to-high titer β₂-glycoprotein-I antibodies).