62 有關骨折癒合（Fracture healing）的描述，何者錯誤？

炎性期（Inflammation），蝕骨細胞（Osteoclasts）及纖維芽細胞（fibroblasts）明顯增生

修補期（Repair），骨折二星期內Soft Callus開始形成，爾後為Hard Callus取代

修飾期（Remodeling）於修補期的中期就開始，可於臨床骨折癒合後持續多年

骨折癒合與病人營養狀況及骨折處固定穩定與否，有相當大的關係

A

• 1. Reactive Phase
  • i. Fracture and inflammatory phase
  • ii. Granulation tissue formation
    • iii. Hematoid (blood clot) formation
• 2. Reparative Phase
  • iii. Cartilage Callus formation
  • iv. Lamellar bone deposition
• 3. Remodeling Phase
  • v. Remodeling to original bone contour

[edit]Reactive

After fracture, the first change seen by light and electron microscopy is the presence of blood cells within the tissues which are adjacent to the injury site. Soon after fracture, the blood vessels constrict, stopping any further bleeding.^[1] Within a few hours after fracture, the extravascular blood cells form a blood clot, known as a hematoma. All of the cells within the blood clot degenerate and die.^[2] Some of the cells outside of the blood clot, but adjacent to the injury site, also degenerate and die.^[3] Within this same area, the fibroblasts survive and replicate. They form a loose aggregate of cells, interspersed with small blood vessels, known as granulation tissue

OSTEOCLAST IS SEEN IN THE REMODELING PHASE