Thursday, November 25, 2010


52 下列有關胰島素的敘述,何者正確?
 含有澱粉的食物在經過胃壁時可誘發胰臟分泌胰島素
在肌肉細胞的細胞膜上有胰島素的受器,當胰島素與其受器接合後,可誘發葡萄糖經過細胞膜進入組織間液
胰臟的β細胞可將葡萄糖代謝後,引起胰島素分泌
胰島素受器有1個α-subunit及2個β-subunits
C

A: AMYLASE
B: INTRACELLULAR NOT INTERSTITIAL
D:Two alpha subunits and two beta subunits make up the insulin receptor.

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55 一位48歲女性有全身性紅斑性狼瘡(SLE)病史,因無月經、躁熱6個月來診,主訴背痛,骨密度檢查用DEXA測量T score -2.5。下列處置何者不適當?
補充足夠鈣質及維他命D 若無禁忌,給予雌性激素補充治療
使用tibolone治療 使用bisphosphonate治療
C

Tibolone is a synthetic steroid hormone drug, which is fairly non-selective in its binding profile, acting as anagonist at all five of the Type I steroid hormone receptors.[1] It is used mainly for treatment of endometriosis,[2]as well as hormone replacement therapy in post-menopausal women.
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58 一位20歲男性病人,因為第二性徵不明顯而來求診。他的身高178公分,體重70公斤,沒有鬍子、腋毛及陰毛稀少、睪丸小而硬。此病人經下列各項檢查,那一種結果最有可能?
FSH值偏低 Testosterone仍在正常範圍
染色體檢查不正常 嗅覺異常
C

NOTE:陰毛稀少、睪丸小而硬
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63 一位65歲男性,有糖尿病之病史,其右腳趾受傷後傷口流膿,傷口細菌培養為ORSA(oxacillin- resistant Staphylococcus aureus)。下列那一種抗生素不適合?
Vancomycin Meropenem Linezolid Daptomycin

MEROPENEM FOR ORSA


MRSA:
Several newly discovered strains of MRSA show antibiotic resistance even to vancomycin and teicoplanin. These new evolutions of the MRSA bacterium have been dubbed Vancomycin intermediate-resistant Staphylococcus aureus (VISA).[60] [61] Linezolid, quinupristin/dalfopristin(synercid), daptomycin, andtigecycline are used to treat more severe infections that do not respond to glycopeptides such as vancomycin.[62]

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