Tuesday, November 23, 2010

70 下列有關初級淋巴器官(primary lymphoid organ)之敘述,何者錯誤?
含有淋巴幹細胞(lymphoid stem cell)
包含胎兒肝(fetal liver)、骨髓、胸腺
除去辨識自我抗原(autoantigen)之淋巴細胞的場所
接受抗原刺激之場所
D

Primary lymphoid organs

The central or primary lymphoid organs generate lymphocytes from immature progenitor cells.

The thymus and the bone marrow constitute the primary lymphoid tissues involved in the production and early selection of lymphocytes.

[edit]Secondary lymphoid organs

Secondary or peripheral lymphoid organs maintain mature naive lymphocytes and initiate an adaptive immune response. The peripheral lymphoid organs are the sites of lymphocyte activation by antigen. Activation leads to clonal expansion and affinity maturation. Mature Lymphocytes recirculate between the blood and the peripheral lymphoid organs until they encounter their specific antigen.

Secondary lymphoid tissue provides the environment for the foreign or altered native molecules (antigens) to interact with the lymphocytes. It is exemplified by the lymph nodes, and the lymphoid follicles in tonsils, Peyer's patches, spleen, adenoids, skin, etc. that are associated with the mucosa-associated lymphoid tissue (MALT).

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