Thursday, November 25, 2010

3 一位病人接受腎移植後服用環孢靈(cyclosporine),下列何種藥物應避免使用?
Allopurinol 紅黴素(erythromycin)
阿斯匹靈(aspirin) 氫離子幫浦抑制劑(proton pump inhibitor)
A/B


THE CYP3A4 INHIBITOR: INCREASE THE CYCLOSPORINE CONCENTRATION IN BLOOD
THESE ARE: ERYTHROMYCIN, ALLOPURINOL,CLARITHROMYCIN, METOCLOPROMIDE

CAME + ANTIFUNGAL + CCB
CCB + CYCLOSPORINE = GINGIVAL HYPERPLASIA
METHYPREDNISOLONE + CYCLOSPRINE = SEIZURE
grape juice does the same thing to increase cyclosporine concentration!!!!!!

THE CYP3A4 AGONIST:decrease cyclosporine concentration in blood
RIFAMPICIN, CARBAMAZEPINE, PHENOBARBITAL, PHENYTOIN

No comments: